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DAPE: a web server to detect homorepeats and follow their evolution.

ABSTRACT: Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats.dAPE can be accessed from http://cbdm-01.zdv.uni-mainz.de/?munoz/polyx .munoz@uni-mainz.de.Supplementary data are available at Bioinformatics online.

SUBMITTER: Mier P

PROVIDER: S-EPMC5408840 | biostudies-other | 2017 Apr

REPOSITORIES: biostudies-other

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dAPE: a web server to detect homorepeats and follow their evolution.

Mier Pablo P Andrade-Navarro Miguel A MA

Bioinformatics (Oxford, England) 20170401 8

<h4>Summary</h4>Homorepeats are low complexity regions consisting of repetitions of a single amino acid residue. There is no current consensus on the minimum number of residues needed to define a functional homorepeat, nor even if mismatches are allowed. Here we present dAPE, a web server that helps following the evolution of homorepeats based on orthology information, using a sensitive but tunable cutoff to help in the identification of emerging homorepeats.<h4>Availability and implementation</ ...[more]

PMID: 28031183

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