Ontology highlight
ABSTRACT:
SUBMITTER: Xi J
PROVIDER: S-EPMC5411169 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Xi Juqun J Da Lanyue L Yang Changshui C Chen Rui R Gao Lizeng L Fan Lei L Han Jie J
International journal of nanomedicine 20170424
Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn<sup>2+</sup>-coordinated doxorubicin (DOX)-loaded poly(lactic-<i>co</i>-glycolic acid) (PLGA) nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA) nanoparticles were first synthesized through a double emulsion-solvent evaporation method, ...[more]