Ontology highlight
ABSTRACT:
SUBMITTER: Stanley SL
PROVIDER: S-EPMC54244 | biostudies-other | 1990 Jul
REPOSITORIES: biostudies-other
Stanley S L SL Becker A A Kunz-Jenkins C C Foster L L Li E E
Proceedings of the National Academy of Sciences of the United States of America 19900701 13
Entamoeba histolytica causes amebic dysentery and amebic liver abscess, major causes of morbidity and mortality worldwide. We have used differential hybridization screening to isolate an E. histolytica-specific cDNA clone. The cDNA was found to encode a serine-rich E. histolytica protein (SREHP) containing multiple tandem repeats. The structural motif of SREHP resembles some of the repetitive antigens of malarial species, especially the circumsporozoite proteins. A recombinant trpE fusion protei ...[more]