Ontology highlight
ABSTRACT:
SUBMITTER: Hudac CM
PROVIDER: S-EPMC5446693 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Hudac Caitlin M CM Stessman Holly A F HAF DesChamps Trent D TD Kresse Anna A Faja Susan S Neuhaus Emily E Webb Sara Jane SJ Eichler Evan E EE Bernier Raphael A RA
Journal of neurodevelopmental disorders 20170526
<h4>Background</h4>Autism spectrum disorder (ASD) is a genetically and phenotypically heterogeneous disorder. Promising initiatives utilizing interdisciplinary characterization of ASD suggest phenotypic subtypes related to specific likely gene-disrupting mutations (LGDMs). However, the role of functionally associated LGDMs in the neural social phenotype is unknown.<h4>Methods</h4>In this study of 26 children with ASD (<i>n</i> = 13 with an LGDM) and 13 control children, we characterized patterns ...[more]