Ontology highlight
ABSTRACT:
SUBMITTER: Ackloo S
PROVIDER: S-EPMC5453191 | biostudies-other | 2017 May
REPOSITORIES: biostudies-other
Ackloo Suzanne S Brown Peter J PJ Müller Susanne S
Epigenetics 20170112 5
Epigenetic chemical probes are potent, cell-active, small molecule inhibitors or antagonists of specific domains in a protein; they have been indispensable for studying bromodomains and protein methyltransferases. The Structural Genomics Consortium (SGC), comprising scientists from academic and pharmaceutical laboratories, has generated most of the current epigenetic chemical probes. Moreover, the SGC has shared about 4 thousand aliquots of these probes, which have been used primarily for phenot ...[more]