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ModelFinder: fast model selection for accurate phylogenetic estimates.


ABSTRACT: Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates by incorporating a model of rate heterogeneity across sites not previously considered in this context and by allowing concurrent searches of model space and tree space.

SUBMITTER: Kalyaanamoorthy S 

PROVIDER: S-EPMC5453245 | biostudies-other | 2017 Jun

REPOSITORIES: biostudies-other

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ModelFinder: fast model selection for accurate phylogenetic estimates.

Kalyaanamoorthy Subha S   Minh Bui Quang BQ   Wong Thomas K F TKF   von Haeseler Arndt A   Jermiin Lars S LS  

Nature methods 20170508 6


Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates by incorporating a model of rate heterogeneity across sites not previously considered in this context and by allowing concurrent searches of model space and tree space. ...[more]

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