Ontology highlight
ABSTRACT:
SUBMITTER: Solzak JP
PROVIDER: S-EPMC5460220 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Solzak Jeffrey P JP Atale Rutuja V RV Hancock Bradley A BA Sinn Anthony L AL Pollok Karen E KE Jones David R DR Radovich Milan M
NPJ breast cancer 20170426
Triple negative breast cancer accounts for 15-20% of all breast cancer cases, but despite its lower incidence, contributes to a disproportionately higher rate of mortality. As there are currently no Food and Drug Administration-approved targeted agents for triple negative breast cancer, we embarked on a genomic-guided effort to identify novel targeted modalities. Analyses by our group and The Cancer Genome Atlas have identified activation of the PI3K-pathway in the majority of triple negative br ...[more]