Ontology highlight
ABSTRACT:
SUBMITTER: Deleye S
PROVIDER: S-EPMC5470082 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Deleye Steven S Waldron Ann-Marie AM Richardson Jill C JC Schmidt Mark M Langlois Xavier X Stroobants Sigrid S Staelens Steven S
Molecular imaging 20160211
<h4>Introduction</h4>In this study, the influence of physiological determinants on 18F-fluoro-d-glucose ((18)F-FDG) brain uptake was evaluated in a mouse model of Alzheimer disease.<h4>Materials and methods</h4>TASTPM (Tg) and age-matched C57BL/6 J (WT) mice were fasted for 10 hours, while another group was fasted for 20 hours to evaluate the effect of fasting duration. The effect of repeatedly scanning was evaluated by scanning Tg and WT mice at days 1, 4, and 7. Brain (18)F-FDG uptake was eval ...[more]