Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5473810 | biostudies-other | 2017 Jun
REPOSITORIES: biostudies-other
Zhang Yadan Y Morgan Ben J BJ Smith Rachel R Fellows Christopher R CR Thornton Catherine C Snow Martyn M Francis Lewis W LW Khan Ilyas M IM
Scientific reports 20170616 1
Platelet-rich plasma (PRP) is used to stimulate the repair of acute and chronic cartilage damage even though there is no definitive evidence of how this is achieved. Chondrocytes in injured and diseased situations frequently re-express phenotypic biomarkers of immature cartilage so tissue maturation is a potential pathway for restoration of normal structure and function. We used an in vitro model of growth factor-induced maturation to perform a comparative study in order to determine whether PRP ...[more]