Ontology highlight
ABSTRACT:
SUBMITTER: Xiong F
PROVIDER: S-EPMC5481830 | biostudies-other | 2017 Jun
REPOSITORIES: biostudies-other
Nature communications 20170619
Synthetic methods inspired by Nature often offer unique advantages including mild conditions and biocompatibility with aqueous media. Inspired by an ergothioneine biosynthesis protein EgtB, a mononuclear non-haem iron enzyme capable of catalysing the C-S bond formation and sulfoxidation, herein, we discovered a mild and metal-free C-H sulfenylation/intramolecular rearrangement cascade reaction employing an internally oxidizing O-N bond as a directing group. Our strategy accommodates a variety of ...[more]