A Historical Review of Diachrony and Semantic Dimensions of Trace in Neurosciences and Lacanian Psychoanalysis.
Ontology highlight
ABSTRACT:
SUBMITTER: Escobar C
PROVIDER: S-EPMC5481870 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Similar Datasets
Project description:Given their strong affinity for the skeleton, trace elements are often stored in bones and teeth long term. Diet, geography, health, disease, social status, activity, and occupation are some factors which may cause differential exposure to, and uptake of, trace elements, theoretically introducing variability in their concentrations and/or ratios in the skeleton. Trace element analysis of bioarchaeological remains has the potential, therefore, to provide rich insights into past human lifeways. This review provides a historical overview of bioarchaeological trace element analysis and comments on the current state of the discipline by highlighting approaches with growing momentum. Popularity for the discipline surged following preliminary studies in the 1960s to 1970s that demonstrated the utility of strontium (Sr) as a dietary indicator. During the 1980s, Sr/Ca ratio and multi-element studies were commonplace in bioarchaeology, linking trace elements with dietary phenomena. Interest in using trace elements for bioarchaeological inferences waned following a period of critiques in the late 1980s to 1990s that argued the discipline failed to account for diagenesis, simplified complex element uptake and regulation processes, and used several unsuitable elements for palaeodietary reconstruction (e.g. those under homeostatic regulation, those without a strong affinity for the skeleton). In the twenty-first century, trace element analyses have been primarily restricted to Sr and lead (Pb) isotope analysis and the study of toxic trace elements, though small pockets of bioarchaeology have continued to analyse multiple elements. Techniques such as micro-sampling, element mapping, and non-traditional stable isotope analysis have provided novel insights which hold the promise of helping to overcome limitations faced by the discipline.Supplementary informationThe online version contains supplementary material available at 10.1007/s12520-020-01262-4.
| S-EPMC7810633 | biostudies-literature
Project description:What determines where we look? Theories of attentional guidance hold that image features and task demands govern fixation behavior, while differences between observers are interpreted as a "noise-ceiling" that strictly limits predictability of fixations. However, recent twin studies suggest a genetic basis of gaze-trace similarity for a given stimulus. This leads to the question of how individuals differ in their gaze behavior and what may explain these differences. Here, we investigated the fixations of >100 human adults freely viewing a large set of complex scenes containing thousands of semantically annotated objects. We found systematic individual differences in fixation frequencies along six semantic stimulus dimensions. These differences were large (>twofold) and highly stable across images and time. Surprisingly, they also held for first fixations directed toward each image, commonly interpreted as "bottom-up" visual salience. Their perceptual relevance was documented by a correlation between individual face salience and face recognition skills. The set of reliable individual salience dimensions and their covariance pattern replicated across samples from three different countries, suggesting they reflect fundamental biological mechanisms of attention. Our findings show stable individual differences in salience along a set of fundamental semantic dimensions and that these differences have meaningful perceptual implications. Visual salience reflects features of the observer as well as the image.
| S-EPMC6576124 | biostudies-literature
Project description:Aesthetic emotions are elicited by different sensory impressions generated by music, visual arts, literature, theater, film, or nature scenes. Recently, the AESTHEMOS scale has been developed to facilitate the empirical assessment of such emotions. In this article we report a semantic profile analysis of aesthetic emotion terms that had been used for the development of this scale, using the GRID approach. This method consists of obtaining ratings of emotion terms on a set of meaning facets (features) which represent five components of the emotion process (appraisal, bodily reactions, action tendencies, expression, and feelings). The aims here were (a) to determine the dimensionality of the GRID features when applied to aesthetic emotions and compare it to published results for emotion terms in general, and (b) to examine the internal organization of the domain of aesthetic emotion terms in order to identify salient clusters of these items based on the similarity of their feature profiles on the GRID. Exploratory Principal Component Analyses suggest a four-dimensional structure of the semantic space consisting of valence, power, arousal, and novelty, converging with earlier GRID studies on large sets of standard emotion terms. Using cluster analyses, 15 clusters of aesthetic emotion terms with similar GRID feature profiles were identified, revealing the internal organization of the aesthetic emotion terms domain and meaningful subgroups of aesthetic emotions. While replication for further languages is required, these findings provide a solid basis for further research and methodological development in the realm of aesthetic emotions.
| S-EPMC8194692 | biostudies-literature
Project description:Throughout history, ancient human societies exploited mineral resources all over the world, even in areas that are now protected and considered to be relatively pristine. Here, we show that past mining still has an impact on wildlife in some French protected areas. We measured cadmium, copper, lead, and zinc concentrations in topsoils and wood mouse kidneys from sites located in the Cévennes and the Morvan. The maximum levels of metals in these topsoils are one or two orders of magnitude greater than their commonly reported mean values in European topsoils. The transfer to biota was effective, as the lead concentration (and to a lesser extent, cadmium) in wood mouse kidneys increased with soil concentration, unlike copper and zinc, providing direct evidence that lead emitted in the environment several centuries ago is still bioavailable to free-ranging mammals. The negative correlation between kidney lead concentration and animal body condition suggests that historical mining activity may continue to play a role in the complex relationships between trace metal pollution and body indices. Ancient mining sites could therefore be used to assess the long-term fate of trace metals in soils and the subsequent risks to human health and the environment.
| S-EPMC5821829 | biostudies-other
Project description:A major issue in human olfaction research is to characterize the main dimensions that organize the space of odors. The present study examines this question and shows that, beside pleasantness, trigeminal sensations, and particularly irritation, play an important role. These results were consistent along two different spaces constructed using semantic description and physiological responses to 105 odorants, smelled and described by human participants. Taken together, these findings suggest that salient trigeminal features, in conjunction with pleasantness, are involved in detecting relevant emotional stimuli, and modify the way organisms categorize smells. These results shed light on the importance of trigeminal sensitivity in the well-established defensive function of olfaction.
| S-EPMC5981304 | biostudies-literature
Project description:Aim: This historical medical literature review aims at understanding the evolution of the medical existence of oral cancer over times, particularly better comprehending if the apparent lower prevalence of this type of cancer in antiquity is a real value due to the absence of modern environmental and lifestyle factors or it is linked to a misinterpretation of ancient foreign terms found in ancient medical texts regarding oral neoplasms. Methods: The databases MedLne, PubMed, Web of Science, Elsevier's EMBASE.com, Cochrane Review, National Library of Greece (Stavros Niarchos Foundation, Athens) and the Library of the School of Health Sciences of the National and Kapodistrian University of Athens (Greece) were extensively searched for relevant studies published during the past century on the history of oral cancer and its treatment from antiquity to modern times, in addition to the WHO website to analyse the latest epidemiological data. In addition, we included historical books on the topic of interest and original sources. Results: Historical references reveal that the cradle of the oral oncology was in ancient Egypt, the Asian continent and Greece and cancer management was confined to an approximate surgical practice, in order to remove abnormal masses and avoid bleeding with cauterization. In the Medieval Age, little progress occurred in medicine in general, oral cancers management included. It is only from the Renaissance to modern times that knowledge about its pathophysiological mechanisms and histopathology and its surgical and pharmacological treatment approaches became increasingly deep all over the world, evolving to the actual integrated treatment. Despite the abundant literature exploring oncology in past civilizations, the real prevalence of oral cancer in antiquity is much less known; but a literature analysis cannot exclude a consistent prevalence of this cancer in past populations, probably with a likely lower incidence than today, because many descriptions of its aggressiveness were found in ancient medical texts, but it is still difficult to be sure that each single description of oral masses could be associated to cancer, particularly for what concerns the period before the Middle Ages. Conclusions: Modern oncologists and oral surgeons must learn a lot from their historic counterparts in order to avoid past unsuccessful efforts to treatment oral malignancies. Several descriptions of oral cancers in the antiquity that we found let us think that this disease might be linked to mechanisms not strictly dependent on environmental risk factors, and this might guide future research on oral cavity treatments towards strategical cellular and molecular techniques.
| S-EPMC7246763 | biostudies-literature
Project description:The treatment of war wounds is an ancient art, constantly refined to reflect improvements in weapons technology, transportation, antiseptic practices, and surgical techniques. Throughout most of the history of warfare, more soldiers died from disease than combat wounds, and misconceptions regarding the best timing and mode of treatment for injuries often resulted in more harm than good. Since the 19th century, mortality from war wounds steadily decreased as surgeons on all sides of conflicts developed systems for rapidly moving the wounded from the battlefield to frontline hospitals where surgical care is delivered. We review the most important trends in US and Western military trauma management over two centuries, including the shift from primary to delayed closure in wound management, refinement of amputation techniques, advances in evacuation philosophy and technology, the development of antiseptic practices, and the use of antibiotics. We also discuss how the lessons of history are reflected in contemporary US practices in Iraq and Afghanistan.
| S-EPMC2706344 | biostudies-other
Project description:PURPOSE:There is a lack of agreement regarding the types of lesions and clinical conditions that should be included in the term "geographic atrophy." Varied and conflicting views prevail throughout the literature and are currently used by retinal experts and other health care professionals. METHODS:We reviewed the nominal definition of the term "geographic atrophy" and conducted a search of the ophthalmologic literature focusing on preceding terminologies and the first citations of the term "geographic atrophy" secondary to age-related macular degeneration. RESULTS:According to the nominal definition, the term "geography" stands for a detailed description of the surface features of a specific region, indicating its relative position. However, it does not necessarily imply that the borders of the region must be sharply demarcated or related to any anatomical structures. The term "geographical areas of atrophy" was initially cited in the 1960s in the ophthalmologic literature in the context of uveitic eye disease and shortly thereafter also for the description of variants of "senile macular degeneration." However, no direct explanation could be found in the literature as to why the terms "geographical" and "geographic" were chosen. Presumably the terms were used as the atrophic regions resembled the map of a continent or well-defined country borders on thematic geographical maps. With the evolution of the terminology, the commonly used adjunct "of the retinal pigment epithelium" was frequently omitted and solely the term "geographic atrophy" prevailed for the nonexudative late-stage of age-related macular degeneration itself. Along with the quantification of atrophic areas, based on different imaging modalities and the use of both manual and semiautomated approaches, various and inconsistent definitions for the minimal lesion diameter or size of atrophic lesions have also emerged. CONCLUSION:Reconsideration of the application of the term "geographic atrophy" in the context of age-related macular degeneration seems to be prudent given ongoing advances in multimodal retinal imaging technology with identification of various phenotypic characteristics, and the observation of atrophy development in eyes under antiangiogenic therapy.
| S-EPMC5115977 | biostudies-literature
Project description:Quarterly time series of the microbial community in the San Pedro Channel
| PRJEB12234 | ENA
Project description:The anterior temporal lobe (ATL) is engaged in various types of semantic dimensions. One consistently reported dimension is social information, with abstract words describing social behaviors inducing stronger activations in the ATL than nonsocial words. One potential factor that has been systematically confounded in this finding is emotional valence, given that abstract social words tend to be associated with emotional feelings. We investigated which factors drove the ATL sensitivity using a 2 (social/nonsocial)?×?2 (valenced/neutral) factorial design in an fMRI study with relatively high spatial resolutions. We found that sociality and valence were processed in different ATL regions without significant interactions: The social effect was found in the left anterior superior temporal sulcus (aSTS), whereas the valence effect activated small clusters in the bilateral temporal poles (TP). In the left ATL, the social- and valence-related clusters were distinct from another superior ATL area that exhibited a general "abstractness" effect with little modulation of sociality or valence. These subregions exhibited distinct whole-brain functional connectivity patterns during the resting state, with the social cluster functionally connected to the default mode network, the valence cluster connected to the adjacent temporal regions and amygdala, and the abstractness cluster connected to a distributed network including a set of language-related regions. These results of activation profiles and connectivity patterns together indicate that the way in which the left ATL supports semantic processing is highly fine-grained, with the neural substrate for social semantic effects dissociated from those for emotional valence and abstractness.
| S-EPMC6865632 | biostudies-literature