Ontology highlight
ABSTRACT:
SUBMITTER: Cruz-Monteagudo M
PROVIDER: S-EPMC5487293 | biostudies-other | 2017 Jul
REPOSITORIES: biostudies-other
Cruz-Monteagudo Maykel M Schürer Stephan S Tejera Eduardo E Pérez-Castillo Yunierkis Y Medina-Franco José L JL Sánchez-Rodríguez Aminael A Borges Fernanda F
Drug discovery today 20170306 7
Current advances in systems biology suggest a new change of paradigm reinforcing the holistic nature of the drug discovery process. According to the principles of systems biology, a simple drug perturbing a network of targets can trigger complex reactions. Therefore, it is possible to connect initial events with final outcomes and consequently prioritize those events, leading to a desired effect. Here, we introduce a new concept, 'Systemic Chemogenomics/Quantitative Structure-Activity Relationsh ...[more]