Ontology highlight
ABSTRACT:
SUBMITTER: Jones KR
PROVIDER: S-EPMC54892 | biostudies-other | 1990 Oct
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19901001 20
Cell death within the developing vertebrate nervous system is regulated in part by interactions between neurons and their innervation targets that are mediated by neurotrophic factors. These factors also appear to have a role in the maintenance of the adult nervous system. Two neurotrophic factors, nerve growth factor and brain-derived neurotrophic factor, share substantial amino acid sequence identity. We have used a screen that combines polymerase chain reaction amplification of genomic DNA an ...[more]