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Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis.

ABSTRACT: The data presented in this brief report support the research article "Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis" [1, doi: 10.1016/j.bbadis.2017.04.006]. We tested whether the absence of Lipocalin-2 (LCN2) could dysregulate the phosphatidylinositol 3-kinase/protein kinase B (PI3K-PKB) pathway and hepatic homeostasis in Non-Alcoholic-Steatohepatitis (NASH). The article highlights the role of LCN2 in hepatic homeostasis.

SUBMITTER: Asimakopoulou A 

PROVIDER: S-EPMC5503832 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other

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Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis.

Asimakopoulou Anastasia A   Borkham-Kamphorst Erawan E   de Leur Eddy Van EV   Weiskirchen Ralf R  

Data in brief 20170701

The data presented in this brief report support the research article "<i>Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis</i>" [1, doi: 10.1016/j.bbadis.2017.04.006]. We tested whether the absence of Lipocalin-2 (LCN2) could dysregulate the phosphatidylinositol 3-kinase/protein kinase B (PI3K-PKB) pathway and hepatic homeostasis in Non-Alcoholic-Steatohepatitis (NASH). The article highlights the role of LCN2 in hepatic homeostasis. ...[more]

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