Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release.

ABSTRACT: Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.

SUBMITTER: Pallavicini P 

PROVIDER: S-EPMC5507905 | biostudies-other | 2017 Jul

REPOSITORIES: biostudies-other