Ontology highlight
ABSTRACT:
SUBMITTER: Tafuri SR
PROVIDER: S-EPMC55094 | biostudies-other | 1990 Nov
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19901101 22
We describe the cloning and characterization of two cDNAs from Xenopus laevis that encode sequence-specific DNA binding proteins called FRG Y1 and FRG Y2 (frog Y-box proteins 1 and 2). During oogenesis and embryogenesis, the genes encoding these proteins are differentially expressed. FRG Y1 mRNA is present in oocytes, embryos, and all adult tissues examined, whereas FRG Y2 mRNA is found only in testis and immature oocytes. The FRG Y1 and FRG Y2 proteins are shown to stimulate transcription from ...[more]