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Stereoacuity after Wavefront-guided Photorefractive Keratectomy in Anisometropia.

ABSTRACT: To determine changes in stereoacuity in anisometropic myopic eyes after photorefractive keratectomy (PRK).Myopic patients with at least 1 diopter (D) of anisometropia in sphere, astigmatism, or spherical equivalent who were referred to our hospital for excimer refractive surgery were enrolled as a prospective sequential interventional case series. All patients underwent wavefront-guided photorefractive keratectomy (WFG-PRK) using the Technolas Perfect Vision (217z) Excimer laser machine. Changes in binocular stereoacuity were evaluated using the TNO and Butterfly stereoacuity tests before and at 2 weeks, 1 month, and 3 months after the operation.Between January and November 2015, a total of 98 eyes of 49 patients (71.4% men) with a mean age of 28 ± 5.5 years, mean myopia of -3.32 ± 1.74 D, and mean astigmatism of 1.3 ± 1.3 D were enrolled in this study. Preoperative mean stereoacuity values were 102 ± 103.44 and 56.8 ± 41 seconds of arc (s/arc)as measured by the TNO and Butterfly stereoacuity tests. Mean stereoacuity improved to 90 ± 110.52 s/arc (P = 0.009) and 56.5 ± 41.3 s/arc (P = 0.80), respectively, 6 months after WFG-PRK. Overall improvement in stereoacuity was 10.2% and 6.12% according to the TNO and Butterfly stereoacuity tests, respectively.Stereoacuity improves after WFG-PRK for treatment of anisometropic myopia. This improvement is more accurately detectable by the TNO than the Butterfly stereoacuity test.

SUBMITTER: Karimian F

PROVIDER: S-EPMC5525494 | biostudies-other | 2017 Jul-Sep

REPOSITORIES: biostudies-other

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Project description:Purpose of the studyTo compare visual outcome, higher order aberrations (HOAs) of topography guided and Q value adjusted ablation in the fellow eye of patients undergoing photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism.MethodsProspective randomized controlled interventional clinical study. The eyes of 52 patients undergoing PRK for myopia and astigmatism were included, that is, 104 eyes in total. In each patient, eyes were randomly allocated to group I: one eye received topography guided PRK using Contoura ablation software, or group II: the other eye received Q value adjusted PRK using Custom Q ablation software.Follow-upSix months.ResultsAt the end of 6 months, LogMAR UDVA was -0.04 ± 0.12 and -0.05 ± 0.11 (p = 0.688), while LogMAR CDVA was -0.06 ± 0.09 and -0.06 ± 0.1 in group I and group II, respectively (p = 0.972). Both groups showed a progressive oblate shift with time. This oblate shift was insignificantly less in group I by Topolyzer at 6mm, 15° and 30° at 6 months (p = 0.102, p = 0.138, p = 0.245, respectively). Topolyzer identified a significant difference between the change in coma and trefoil in both groups at 6 months (p<0.001 and p = 0.001, respectively). This was caused by the significant worsening of coma in group II (p<0.001) and the significant improvement of trefoil in group I (p = 0.007). No significant difference was found between groups in the change of ISV or ABR (p = 0.955 and 0.982, respectively). Ablation depth is a significant predictor of ΔQ at 6mm, 15° and 30° (p = 0.009, 0.039 and 0, respectively). No significant difference was found in the Strehl ratio or contrast sensitivity, although they were insignificantly better in group I (p = 0.785 and p = 0.745, respectively).ConclusionTG PRK and CQ PRK yielded similar results regarding UDVA, CDVA, MRSE, safety, predictability and contrast sensitivity. Both groups showed a progressive oblate shift, which was less in the TG group but the difference was statistically insignificant. TG PRK showed significantly improved trefoil HOA as compared to CQ PRK.

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Stereoacuity after Wavefront-guided Photorefractive Keratectomy in Anisometropia.

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