Ontology highlight
ABSTRACT:
SUBMITTER: Almegren M
PROVIDER: S-EPMC5529093 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Vascular health and risk management 20170719
Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a major concern in clinical practice. After DOACs were introduced and became widely used as an alternative for vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation, the need for effective reversal agents has increased, particularly for life-threatening bleeding episodes related to DOACs or to reverse medication effects during u ...[more]