Ontology highlight
ABSTRACT:
SUBMITTER: Kim JI
PROVIDER: S-EPMC5537907 | biostudies-other | 2017 Jul
REPOSITORIES: biostudies-other
Kim Jin-Il JI Jeon Seong Gak SG Kim Kyoung Ah KA Kim Jwa-Jin JJ Song Eun Ji EJ Jeon Yukyoung Y Kim Eunbin E Lee Kyung Bok KB Kwak Jong Hwan JH Moon Minho M
Nutrients 20170723 7
<i>Platycodon grandiflorus</i> (Jacq.) A.DC. (PG) has long been used as an ingredient of foods and is known to have beneficial effects on cognitive functions as well. The present study examined the effect of each PG extract (PGE) from root, aerial part, and seeds on cognitive functions in mice. Changes in spatial learning and memory using a Y-maze test, and markers of adult hippocampal neurogenesis and synaptogenesis were examined. Moreover, changes in neuritogenesis and activation of the ERK1/2 ...[more]