A catch and release program for single-stranded DNA.

ABSTRACT: Uncovering the mechanisms by which single-stranded binding proteins both protect and expose single-stranded DNA has important implications for our understanding of DNA replication and repair. A new study serves up a master class in developing a full kinetic model for one such protein, mtSSB, showing how DNA can be reeled in and set free to control accessibility.

SUBMITTER: Eoff RL 

PROVIDER: S-EPMC5546045 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other