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Opening a Chromatin Gate to Metastasis.


ABSTRACT: What changes need to occur in a primary tumor to make it metastatic? Denny et al. address this question for small cell lung cancer (SCLC), finding that changes in genomic accessibility mediated by a single transcription factor, NFIB, comprise at least one mechanism influencing metastasis.

SUBMITTER: Minna JD 

PROVIDER: S-EPMC5546407 | biostudies-other | 2016 Jul

REPOSITORIES: biostudies-other

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