Redox Paradox: Can Hypoxia Heal Ischemic Hearts?

ABSTRACT: Adult cardiomyocytes are largely thought to lack proliferative and therefore regenerative potential. Reporting in Nature, Nakada et al. (2016) find that a hypoxic regime reduces mitochondrial metabolism and promotes proliferation in adult mouse cardiomyocytes, resulting in increased regeneration following myocardial infarction. These findings suggest the potential to transform post-MI care.

SUBMITTER: Guimaraes-Camboa N 

PROVIDER: S-EPMC5547440 | biostudies-other | 2016 Nov

REPOSITORIES: biostudies-other