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Ocular Infection: Endophthalmitis.

ABSTRACT: Endophthalmitis is characterized by marked inflammation of intraocular fluids and tissues. Infective endophthalmitis may be categorized by the cause of the infection, which helps predict the underlying etiology and most likely causative organisms. The major category remains acute-onset postoperative endophthalmitis. Infective endophthalmitis is a clinical diagnosis but is confirmed by evaluation of intraocular fluid specimens. The Endophthalmitis Vitrectomy Study offered important guidelines for the initial management of endophthalmitis, and these guidelines remain relevant to this day. Prompt initiation of empiric broad-spectrum antimicrobial therapy is important in achieving best outcomes.

SUBMITTER: Schwartz SG

PROVIDER: S-EPMC5548375 | biostudies-other | 2016

REPOSITORIES: biostudies-other

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In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection

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2015-09-12 | E-MTAB-2928 | biostudies-arrayexpress

In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection.

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Human Endophthalmitis Caused By Pseudorabies Virus Infection, China, 2017.

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Prognostic Utility of Whole-Genome Sequencing and Polymerase Chain Reaction Tests of Ocular Fluids in Postprocedural Endophthalmitis.

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Bacterial Burden Declines But Neutrophil Infiltration and Ocular Tissue Damage Persist in Experimental <i>Staphylococcus epidermidis</i> Endophthalmitis.

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Ocular Findings in Yellow Fever Infection.

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Temporal retinal transcriptome analysis in Staphylococcus aureus endophthalmitis

Project description:Bacterial endophthalmitis remains a devastating inflammatory disease associated with permanent vision loss. The mechanisms regulating inflammation to protect the eye remain elusive. Therefore, assessing the host immune response in bacterial endophthalmitis may provide new therapeutic targets. We used microarrays to determine the global profiling of up-regulated and downregulated gene expression in bacterial endophthalmitis.

2022-04-08 | GSE200443 | GEO

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