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The Look AHEAD Trial: Translating Lessons Learned Into Clinical Practice and Further Study.


ABSTRACT: IN BRIEF Although the Look AHEAD (Action for Health in Diabetes) trial, which spanned more than 8 years, did not find significant differences in cardiovascular morbidity and mortality between study groups, it did demonstrate significant differences in weight loss and maintenance. Using lessons learned from the Look AHEAD protocol, clinicians can help people with type 2 diabetes lose weight, improve glucose management, increase physical activity, alter eating patterns, and support long-term positive health outcomes. It remains important, however, to avoid assigning a higher priority to weight loss goals than to improvements in glucose management, long-term health outcomes, and quality of life.

SUBMITTER: Salvia MG 

PROVIDER: S-EPMC5556585 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other

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The Look AHEAD Trial: Translating Lessons Learned Into Clinical Practice and Further Study.

Salvia Meg G MG  

Diabetes spectrum : a publication of the American Diabetes Association 20170801 3


<b>IN BRIEF</b> Although the Look AHEAD (Action for Health in Diabetes) trial, which spanned more than 8 years, did not find significant differences in cardiovascular morbidity and mortality between study groups, it did demonstrate significant differences in weight loss and maintenance. Using lessons learned from the Look AHEAD protocol, clinicians can help people with type 2 diabetes lose weight, improve glucose management, increase physical activity, alter eating patterns, and support long-ter  ...[more]

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