Tumor evolution in response to chemotherapy: phenotype versus genotype.
Ontology highlight
ABSTRACT: In this issue of Cell Reports, Almendro et al. report one of the first comprehensive studies on the intratumor heterogeneity of cell phenotypes and genotypes before and after chemotherapy in breast cancer. These data challenge the concept of genetic population bottlenecks and suggest that cellular phenotypes play an important role in developing resistance to therapy.
SUBMITTER: Navin NE
PROVIDER: S-EPMC5558200 | biostudies-other | 2014 Feb
REPOSITORIES: biostudies-other
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