Ontology highlight
ABSTRACT:
SUBMITTER: Sissung TM
PROVIDER: S-EPMC5558514 | biostudies-other | 2016 Dec
REPOSITORIES: biostudies-other
Pharmacogenomics 20161124 18
<h4>Aim</h4>Metabolism and transport play major roles in life-long exposure to endogenous and exogenous carcinogens. We therefore explored associations between polymorphisms in absorption, distribution, metabolism and elimination genes and the risk and prognosis of castration-resistant prostate cancer (CRPC).<h4>Materials & methods</h4>A total of 634 genotypes were tested in 74 patients using the Affymetrix DMETv1.0 platform.<h4>Results</h4>No relation to risk was found. Three SNPs were associat ...[more]