Ontology highlight
ABSTRACT:
SUBMITTER: Murphy JA
PROVIDER: S-EPMC5559917 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Murphy Jenifer A JA Sarris Jerome J Byrne Gerard J GJ
Depression research and treatment 20170803
Major depression does not always remit. Difficult-to-treat depression is thought to contribute to the large disease burden posed by depression. Treatment-resistant depression (TRD) is the conventional term for nonresponse to treatment in individuals with major depression. Indicators of the phenomenon are the poor response rates to antidepressants in clinical practice and the overestimation of the efficacy of antidepressants in medical scientific literature. Current TRD staging models are based o ...[more]