Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC5562841 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Liu J J Xue Y Y Dong D D Xiao C C Lin C C Wang H H Song F F Fu T T Wang Z Z Chen J J Pan H H Li Y Y Cai D D Li Z Z
Mucosal immunology 20170125 5
Macrophages are distributed throughout the body and are crucial for the restoration of damaged tissues. However, their characteristics in the cornea and roles in the repair of corneal injures are unclear. Here we show that corneal macrophages can be classified as CCR2<sup>-</sup> macrophages, which already exist in the cornea at embryonic day 12.5 (E12.5) and are similar to yolk sac-derived macrophages, microglia, in phenotype and gene expression, and CCR2<sup>+</sup> macrophages, which do not a ...[more]