Dynamic weight bearing analysis is effective for evaluation of tendinopathy using a customized corridor with multi-directional force sensors in a rat model.
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ABSTRACT:
SUBMITTER: Wu PT
PROVIDER: S-EPMC5562883 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Publications
Dynamic weight bearing analysis is effective for evaluation of tendinopathy using a customized corridor with multi-directional force sensors in a rat model.
Wu Po-Ting PT Hsu Chieh-Hsiang CH Su Fong-Chin FC Jou I-Ming IM Chen Shih-Yao SY Wu Chao-Liang CL Su Wei-Ren WR Kuo Li-Chieh LC
Scientific reports 20170818 1
Few studies discuss kinetic changes in tendinopathy models. We propose a customized corridor to evaluate dynamic weight bearing (DWB) and shearing forces. Sixty rats were randomly given ultrasound-assisted collagenase injections (Collagenase rats) or needle punctures (Control rats) in their left Achilles tendons, and then evaluated 1, 4, and 8 weeks later. The Collagenase rats always had significantly (p < 0.001) higher histopathological and ultrasound feature scores than did the Controls, signi ...[more]
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