Ontology highlight
ABSTRACT:
SUBMITTER: Wan Q
PROVIDER: S-EPMC5567257 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Wan Qiaoqiao Q TruongVo ThucNhi T Steele Hannah E HE Ozcelikkale Altug A Han Bumsoo B Wang Yingxiao Y Oh Junghwan J Yokota Hiroki H Na Sungsoo S
Scientific reports 20170822 1
Focal adhesion kinase (FAK) and Src family kinases (SFK) are known to play critical roles in mechanotransduction and other crucial cell functions. Recent reports indicate that they reside in different microdomains of the plasma membrane. However, little is known about their subcellular domain-dependent roles and responses to extracellular stimuli. Here, we employed fluorescence resonance energy transfer (FRET)-based biosensors in conjunction with collagen-coupled agarose gels to detect subcellul ...[more]