Ontology highlight
ABSTRACT:
SUBMITTER: Kong SY
PROVIDER: S-EPMC5576525 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Kong So Yeon SY Tran Hao Quang HQ Gewirtz Andrew T AT McKeown-Eyssen Gail G Fedirko Veronika V Romieu Isabelle I Tjønneland Anne A Olsen Anja A Overvad Kim K Boutron-Ruault Marie-Christine MC Bastide Nadia N Affret Aurélie A Kühn Tilman T Kaaks Rudolf R Boeing Heiner H Aleksandrova Krasimira K Trichopoulou Antonia A Kritikou Maria M Vasilopoulou Effie E Palli Domenico D Krogh Vittorio V Mattiello Amalia A Tumino Rosario R Naccarati Alessio A Bueno-de-Mesquita H B HB Peeters Petra H PH Weiderpass Elisabete E Quirós J Ramón JR Sala Núria N Sánchez María-José MJ Castaño José María Huerta JM Barricarte Aurelio A Dorronsoro Miren M Werner Mårten M Wareham Nicholas J NJ Khaw Kay-Tee KT Bradbury Kathryn E KE Freisling Heinz H Stavropoulou Faidra F Ferrari Pietro P Gunter Marc J MJ Cross Amanda J AJ Riboli Elio E Bruce W Robert WR Jenab Mazda M
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20160111 2
<h4>Background</h4>Chronic inflammation and oxidative stress are thought to be involved in colorectal cancer development. These processes may contribute to leakage of bacterial products, such as lipopolysaccharide (LPS) and flagellin, across the gut barrier. The objective of this study, nested within a prospective cohort, was to examine associations between circulating LPS and flagellin serum antibody levels and colorectal cancer risk.<h4>Methods</h4>A total of 1,065 incident colorectal cancer c ...[more]