Ontology highlight
ABSTRACT:
SUBMITTER: Shindo K
PROVIDER: S-EPMC5584208 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Shindo Koji K Yu Jun J Suenaga Masaya M Fesharakizadeh Shahriar S Tamura Koji K Almario Jose Alejandro Navarro JAN Brant Aaron A Borges Michael M Siddiqui Abdulrehman A Datta Lisa L Wolfgang Christopher L CL Hruban Ralph H RH Klein Alison Patricia AP Goggins Michael M
Oncotarget 20170207 31
CEL-HYB is a hybrid allele that arose from a crossover between the 3' end of the Carboxyl ester lipase (<i>CEL</i>) gene and the nearby <i>CEL</i> pseudogene (<i>CELP</i>) and was recently identified as a risk factor for chronic pancreatitis. Since chronic pancreatitis is a risk factor for the development of pancreatic cancer, we compared the prevalence of the CEL-HYB allele in patients with pancreatic ductal adenocarcinoma to spousal controls and disease controls. The CEL-HYB allele was detecte ...[more]