Dataset on continuous passages of Trypanosoma brucei in different laboratory animals.

ABSTRACT: Scientist in developing countries maintain trypanosomes in laboratory animals for in vivo experiments. We generated data on the adaptation of Trypanosoma brucei (NITR201 strain) in balb/c mice (forty-five, 18-23 g), wistar rats (fifteen, 180-220 g) and New Zealand white and chinchilla rabbits (fifteen, 2.8-3.0 kg) in a controlled experimental system. The weight, haematological parameters, course of parasitaemia, temperature, mean survival time and survival proportions of laboratory animals in groups A-E were collected and analysed for differences in response to the same challenge of quantity, strain and species of T. brucei. Trypanosome pleomorphism of long, intermediate to short-stumpy forms were among the dataset counts for parasitaemia. Statistical data after analysis were summarised in the supplementary file to show the differences and corresponding reaction of multiple passages.

SUBMITTER: Odeniran PO 

PROVIDER: S-EPMC5587882 | biostudies-other | 2017 Oct

REPOSITORIES: biostudies-other