Ontology highlight
ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC5595820 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Lu Juan J Wang Dan D Shen Jie J
Scientific reports 20170912 1
An appropriate balance between cell survival and cell death is essential for correct pattern formation in the animal tissues and organs. Previous studies have shown that the short-range signalling molecule Hedgehog (Hh) is required for cell proliferation and pattern formation in the Drosophila central wing discs. Signal transduction by one of the Hh targets, the morphogen Decapentaplegic (Dpp), is required for not only cell proliferation, but also cell survival in the pouch cells. However, Hh fu ...[more]