Ontology highlight
ABSTRACT:
SUBMITTER: Qian X
PROVIDER: S-EPMC5595879 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Scientific reports 20170912 1
There is high demand for forensic pedigree searches with Y-chromosome short tandem repeat (Y-STR) profiling in large-scale crime investigations. However, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they are from the same male lineage because of the high mutation rate of Y-STRs. Here we design a new strategy to handle cases in which none of pedigree samples shares identical Y-STR haplotype. We combine next generation sequencing (NGS), capillary electropho ...[more]