Ontology highlight
ABSTRACT:
SUBMITTER: Dhanasekar NN
PROVIDER: S-EPMC5614690 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Dhanasekar Naresh Niranjan NN Aliouane Soumeya S Winterhalter Mathias M Pagès Jean-Marie JM Bolla Jean-Michel JM
Biochemistry and biophysics reports 20170623
Here we report on translocation of short poly-arginines across the MOMP porin, the major outer membrane protein in the cell wall of <i>Campylobacter jejuni</i>. MOMP was purified to homogeneity from a pathogenic strain of <i>C. jejuni</i>. Its reconstitution in lipid membranes and measuring the ion-current revealed two main distinct populations of protein channels which we interpreted as mono and trimers. Addition of poly-arginines causes concentration and voltage dependent ion-current fluctuati ...[more]