Self-Assembly of Human Serum Albumin: A Simplex Phenomenon.
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ABSTRACT:
SUBMITTER: Thakur G
PROVIDER: S-EPMC5618250 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Publications
Self-Assembly of Human Serum Albumin: A Simplex Phenomenon.
Thakur Garima G Prashanthi Kovur K Jiang Keren K Thundat Thomas T
Biomolecules 20170920 3
Spontaneous self-assemblies of biomolecules can generate geometrical patterns. Our findings provide an insight into the mechanism of self-assembled ring pattern generation by human serum albumin (HSA). The self-assembly is a process guided by kinetic and thermodynamic parameters. The generated protein ring patterns display a behavior which is geometrically related to a <i>n</i>-simplex model and is explained through thermodynamics and chemical kinetics. ...[more]
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