Ontology highlight
ABSTRACT:
SUBMITTER: Itakura G
PROVIDER: S-EPMC5636829 | biostudies-other | 2017 Oct
REPOSITORIES: biostudies-other
Itakura Go G Ozaki Masahiro M Nagoshi Narihito N Kawabata Soya S Nishiyama Yuichiro Y Sugai Keiko K Iida Tsuyoshi T Kashiwagi Rei R Ookubo Toshiki T Yastake Kaori K Matsubayashi Kohei K Kohyama Jun J Iwanami Akio A Matsumoto Morio M Nakamura Masaya M Okano Hideyuki H
Scientific reports 20171011 1
Resolving the immunogenicity of cells derived from induced pluripotent stem cells (iPSCs) remains an important challenge for cell transplant strategies that use banked allogeneic cells. Thus, we evaluated the immunogenicity of mouse fetal neural stem/progenitor cells (fetus-NSPCs) and iPSC-derived neural stem/progenitor cells (iPSC-NSPCs) both in vitro and in vivo. Flow cytometry revealed the low expression of immunological surface antigens, and these cells survived in all mice when transplanted ...[more]