The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
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ABSTRACT:
SUBMITTER: Zheng HC
PROVIDER: S-EPMC5641188 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Publications
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Zheng Hua-Chuan HC Gong Bao-Cheng BC Zhao Shuang S
Oncotarget 20170818 42
GRP78 is a molecular chaperone located in endoplasmic reticulum, and induces folding and assembly of newly-synthesized proteins, proteasome degradation of aberrant proteins, and translocation of secretory proteins, autophagy, and epithelial-mesenchymal transition. We performed a systematic meta- and bioinformatics analysis through multiple online databases up to March 14, 2017. It was found that up-regulated GRP78 expression in gastric cancer, compared with normal mucosa at both protein and mRNA ...[more]
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