Ontology highlight
ABSTRACT:
SUBMITTER: Van Wickle JD
PROVIDER: S-EPMC5674246 | biostudies-other | 2017 Oct
REPOSITORIES: biostudies-other
Van Wickle Jonathan D JD Paulson Eric S ES Landry Jerome C JC Erickson Beth A BA Hall William A WA
Journal of gastrointestinal oncology 20171001 5
Total mesorectal excision (TME) after neoadjuvant chemoradiotherapy (CRT) has offered superior control for patients with locally advanced rectal cancer, but can carry a quality of life cost. Fortunately, some patients achieve a complete response after CRT alone without the added morbidity caused by surgery. Efforts to increase fidelity of radiation treatment planning and delivery may allow for escalated doses of radiotherapy (RT) with limited off-target toxicity and elicit more pathological comp ...[more]