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The Triglycerides and Glucose Index rather than HOMA-IR is more associated with Hypogonadism in Chinese men.


ABSTRACT: Previous studies have reported that insulin resistant and low testosterone are related. The triglyceride and glucose index (TyG) well mirrors insulin sensitivity. No study investigated the application of TyG in male hypogonadism. We aimed to explore whether TyG was associated with hypogonadism, and also evaluate the ability of TyG compared to HOMA-IR as a possible hypogonadism predictor. A total of 4299 male subjects were enrolled from 22 sites in East China. Hypogonadism was defined as total testosterone <11.3 nmol/L. 695 (16.2%) hypogonadal men had significantly higher TyG index. The prevalence of hypogonadism stepwise increased across increasing TyG quartiles (P?

SUBMITTER: Zhang K 

PROVIDER: S-EPMC5696537 | biostudies-other | 2017 Nov

REPOSITORIES: biostudies-other

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The Triglycerides and Glucose Index rather than HOMA-IR is more associated with Hypogonadism in Chinese men.

Zhang Kun K   Chen Yi Y   Liu Lijie L   Lu Meng M   Cheng Jing J   Gao Fengbin F   Wang Ningjian N   Shen Zhoujun Z   Lu Yingli Y  

Scientific reports 20171120 1


Previous studies have reported that insulin resistant and low testosterone are related. The triglyceride and glucose index (TyG) well mirrors insulin sensitivity. No study investigated the application of TyG in male hypogonadism. We aimed to explore whether TyG was associated with hypogonadism, and also evaluate the ability of TyG compared to HOMA-IR as a possible hypogonadism predictor. A total of 4299 male subjects were enrolled from 22 sites in East China. Hypogonadism was defined as total te  ...[more]

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