Ontology highlight
ABSTRACT:
SUBMITTER: Sagadevan A
PROVIDER: S-EPMC5703888 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Sagadevan Arunachalam A Hwang Kuo Chu KC Su Ming-Der MD
Nature communications 20171127 1
Singlet O<sub>2</sub> is a key reactive oxygen species responsible for photodynamic therapy and is generally recognized to be chemically reactive towards C=C double bonds. Herein, we report the hydroperoxidation/lactonization of α-ethereal C-H bonds by singlet O<sub>2</sub> (<sup>1</sup>Δ<sub>g</sub>) under exceptionally mild conditions, i.e., room temperature and ambient pressure, with modest to high yields (38~90%) and excellent site selectivity. Singlet O<sub>2</sub> has been known for > 90 y ...[more]