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Risk score for first-screening of prevalent undiagnosed chronic kidney disease in Peru: the CRONICAS-CKD risk score.


ABSTRACT: Chronic Kidney Disease (CKD) represents a great burden for the patient and the health system, particularly if diagnosed at late stages. Consequently, tools to identify patients at high risk of having CKD are needed, particularly in limited-resources settings where laboratory facilities are scarce. This study aimed to develop a risk score for prevalent undiagnosed CKD using data from four settings in Peru: a complete risk score including all associated risk factors and another excluding laboratory-based variables.Cross-sectional study. We used two population-based studies: one for developing and internal validation (CRONICAS), and another (PREVENCION) for external validation. Risk factors included clinical- and laboratory-based variables, among others: sex, age, hypertension and obesity; and lipid profile, anemia and glucose metabolism. The outcome was undiagnosed CKD: eGFR?

SUBMITTER: Carrillo-Larco RM 

PROVIDER: S-EPMC5707893 | biostudies-other | 2017 Nov

REPOSITORIES: biostudies-other

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Risk score for first-screening of prevalent undiagnosed chronic kidney disease in Peru: the CRONICAS-CKD risk score.

Carrillo-Larco Rodrigo M RM   Miranda J Jaime JJ   Gilman Robert H RH   Medina-Lezama Josefina J   Chirinos-Pacheco Julio A JA   Muñoz-Retamozo Paola V PV   Smeeth Liam L   Checkley William W   Bernabe-Ortiz Antonio A  

BMC nephrology 20171129 1


<h4>Background</h4>Chronic Kidney Disease (CKD) represents a great burden for the patient and the health system, particularly if diagnosed at late stages. Consequently, tools to identify patients at high risk of having CKD are needed, particularly in limited-resources settings where laboratory facilities are scarce. This study aimed to develop a risk score for prevalent undiagnosed CKD using data from four settings in Peru: a complete risk score including all associated risk factors and another  ...[more]

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