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Molecular Subtypes and Local-Regional Control of Breast Cancer.


ABSTRACT: In the era of personalized medicine, there has been significant progress regarding the molecular analysis of breast cancer subtypes. Research efforts have focused on how classification of subtypes could provide information on prognosis and influence treatment planning. Although much is known about the impact of different molecular subtypes on disease-specific survival, more recent studies have investigated the role of the different molecular subtypes on local-regional recurrence. This is an area of active study, and in recent years there has been significant progress. This article describes outcomes among disease subtypes to aid in optimal surgical decision-making to improve local-regional control.

SUBMITTER: Fragomeni SM 

PROVIDER: S-EPMC5715810 | biostudies-other | 2018 Jan

REPOSITORIES: biostudies-other

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Molecular Subtypes and Local-Regional Control of Breast Cancer.

Fragomeni Simona Maria SM   Sciallis Andrew A   Jeruss Jacqueline S JS  

Surgical oncology clinics of North America 20180101 1


In the era of personalized medicine, there has been significant progress regarding the molecular analysis of breast cancer subtypes. Research efforts have focused on how classification of subtypes could provide information on prognosis and influence treatment planning. Although much is known about the impact of different molecular subtypes on disease-specific survival, more recent studies have investigated the role of the different molecular subtypes on local-regional recurrence. This is an area  ...[more]

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