Ontology highlight
ABSTRACT:
SUBMITTER: Vail NS
PROVIDER: S-EPMC5718289 | biostudies-other | 2017 Aug
REPOSITORIES: biostudies-other
Vail Nicholas S NS Stubbs Christopher C Biggs Caroline I CI Gibson Matthew I MI
ACS macro letters 20170801 9
Polymer mimics of antifreeze proteins are emerging as an exciting class of macromolecular cryoprotectants for the storage of donor cells and tissue. Poly(vinyl alcohol), PVA, is the most potent polymeric ice growth inhibitor known, but its mode of action and the impact of valency (DP) are not fully understood. Herein, tandem RAFT polymerization and column chromatography are used to isolate oligomers with dispersities <1.01 to enable the effect of molecular weight distribution, as well as length, ...[more]