Ontology highlight
ABSTRACT:
SUBMITTER: Parade SH
PROVIDER: S-EPMC5720139 | biostudies-other | 2017 Dec
REPOSITORIES: biostudies-other
Parade Stephanie H SH Parent Justin J Rabemananjara Kantoniony K Seifer Ronald R Marsit Carmen J CJ Yang Bao-Zhu BZ Zhang Huiping H Tyrka Audrey R AR
Development and psychopathology 20171201 5
FK506 binding protein 5 (FKBP5) alters stress response system functioning, and childhood maltreatment is associated with methylation of the FKBP5 gene. Yet it is unknown if maltreatment contributes to change in FKBP5 methylation over time. The current study draws upon a sample of 231 preschoolers, including 123 with child welfare documentation of moderate to severe maltreatment in the past 6 months, to understand if maltreatment contributes to change in FKBP5 methylation over a 6-month period. R ...[more]