Ontology highlight
ABSTRACT:
SUBMITTER: Del Mar Masdeu M
PROVIDER: S-EPMC5731862 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Oncotarget 20170915 60
Ack1 (activated Cdc42-associated tyrosine kinase) is a non-receptor tyrosine kinase that is highly expressed in brain. This kinase contains several protein-protein interaction domains and its action is partially regulated by phosphorylation. As a first step to address the neuronal functions of Ack1, here we screened mouse brain samples to identify proteins that interact with this kinase. Using mass spectrometry analysis, we identified new putative partners for Ack1 including cytoskeletal protein ...[more]