Ontology highlight
ABSTRACT:
SUBMITTER: Gendarme M
PROVIDER: S-EPMC5739293 | biostudies-other | 2017 Dec
REPOSITORIES: biostudies-other
Gendarme Mathieu M Baumann Jan J Ignashkova Tatiana I TI Lindemann Ralph K RK Reiling Jan H JH
Molecular biology of the cell 20171026 26
The Golgi apparatus is increasingly recognized as a major hub for cellular signaling and is involved in numerous pathologies, including neurodegenerative diseases and cancer. The study of Golgi stress-induced signaling pathways relies on the selectivity of the available tool compounds of which currently only a few are known. To discover novel Golgi-fragmenting agents, transcriptomic profiles of cells treated with brefeldin A, golgicide A, or monensin were generated and compared with a database o ...[more]