Ontology highlight
ABSTRACT:
SUBMITTER: Vinogradov AE
PROVIDER: S-EPMC5742502 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Vinogradov A E AE Shilina M A MA Anatskaya O V OV Alekseenko L L LL Fridlyanskaya I I II Krasnenko A A Kim A A Korostin D D Ilynsky V V Elmuratov A A Tsyganov O O Grinchuk T M TM Nikolsky N N NN
Stem cells international 20171210
High temperature is a critical environmental and personal factor. Although heat shock is a well-studied biological phenomenon, hyperthermia response of stem cells is poorly understood. Previously, we demonstrated that sublethal heat shock induced premature senescence in human endometrial mesenchymal stem cells (eMSC). This study aimed to investigate the fate of eMSC-survived sublethal heat shock (SHS) with special emphasis on their genetic stability and possible malignant transformation using me ...[more]