Ontology highlight
ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC5743838 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Liu Le L Ruan Zheng Z Yuan Pan P Li Tuanwei T Yan Lifeng L
Nanotheranostics 20180101 1
Near infrared (NIR) imaging-guided photodynamic therapy (PDT) is remarkable for its high-efficiency in "see and treat" field. However, hypoxia of cancer cell limits PDT dues to the low singlet oxygen yield. Here MnO<sub>2</sub> conjugated multifunctional polypeptide nanoparticles encapsulating photosensitizer BODIPY has been prepared via a one-step reaction, which can generate oxygen in cancer cytoplasm where rich of H<sub>2</sub>O<sub>2</sub>, following singlet oxygen by photosensitizer under N ...[more]